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Consequently, a number of nucleases have been suggested to function in ICL repair, including MUS81-EME1, XPF-ERCC1 and SLX4-SLX1 (Douwet et al., 2014).
Chromatoid bodies (CBs) are characteristic spermatid organelles, which were suggested to function in RNA storage and small RNA processing but whose functions remain largely unknown.
In addition, another conserved residue, tryptophan-398 was suggested to function in PHA synthase subunit dimerization by the provision of a hydrophobic surface (Gerngross et al., [1994]; Jia et al., [2001]).
C. elegans TRPA-1, the ortholog of the mammalian TRPA1, was suggested to function in mechanosensation [29].
Cep215/Cdk5Rap2 is yet another protein suggested to function in the recruitment of γTuRCs to centrosomes [27].
Binding of the co-activator CBP, a histone acetyl transferase that has also been suggested to function in long-range β-globin gene activation [35], was also nearly the same upon transcription inhibtion (Figure 5D).
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A strictly conserved glutamate residue is suggested to function catalytically in thioester proteins.
With the aforementioned results, the ESP part and bag filter part are suggested to function cooperatively in the hybrid ESP/BAG.
SKC1 was found to encode a sodium transporter that helps control Na+/K+ homeostasis through unloading of Na+ from the xylem (Ren et al. 2005), which has been suggested to function primarily in roots to reduce the amount of Na+ ions that are transported to the leaves (Hauser and Horie 2010).
Serotonin systems have been suggested to function differently in pre and post-pubertal children [ 71].
Since Ach1p has been suggested to function primarily in mitochondria (Fleck and Brock, 2009), we next assessed whether block of AcCoA production through mitochondrial pyruvate dehydrogenase (PDH) pathway would also impair autophagy of aging yeast.
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