Suggestions(5)
Exact(8)
EGFR copy number assessed by FISH has also been suggested to be predictive of clinical outcome to EGFR-targeted therapies [29] [33].
HER2 positivity has been suggested to be predictive for response to certain chemotherapies, including anthracyclines and taxanes [ 16, 17].
In a follow-up study, a synergistic elevation in circulating levels of IL-1β and IL-6 was suggested to be predictive of type 2 diabetes (44).
Individual activity patterns have even been suggested to be predictive of the patients' survival, tumour response and quality of life (Mormont and Levi, 1997; Mormont et al, 2000).
Dyslipidemia [ 6, 14, 15], obesity [ 7, 16] and hyperuricemia [ 17- 20] have also been suggested to be predictive factors for CKD.
and these are also involved in several mendelian randomization analyses in relation to major disease endpoints for which these biomarkers have been suggested to be predictive.
Similar(52)
Similar to the nontransplant settings, impaired glucose metabolism in the pre- and/or posttransplant period has been suggested to be a predictive risk factor for the development of NODAT.
Moreover, a high level of TILs has been suggested to be a predictive factor for pCR in response to PST in breast cancer (Hornychova et al, 2008; Denkert et al, 2010; West et al, 2011; Ono et al, 2012; Lee et al, 2013).
In this approach, the chemoresponse assay is suggested to be a predictive marker when the PFS for sensitive categories (SA, SP) differs from the PFS for non-sensitive categories (RA, RP) and no substantial difference is observed within each category (SA vs SP and RA vs RP).
S100A8 has been suggested to be a predictive biomarker of bladder cancer outcome in several studies [ 21- 23], however, the regulation of S100A8 gene expression and whether the genes associated with its expression provides additional insight into the mechanisms of disease progression or tumor invasion have not been studied.
IDH status has major prognostic implications for patients with diffuse gliomas, and was suggested to be a better predictive factor for benefit to chemotherapy in the RTOG trial on adjuvant PCV chemotherapy in anaplastic oligodendroglial tumors [ 20].
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