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Our results extend previous studies that suggested simultaneous hypo- and hyper-methylation occurred with tumor progression by measuring both in the same tumor cells.
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The resultant PPNH2 and PPNA exhibit reduced crystallinity while the crystallization temperature shifts toward higher values, suggesting simultaneous effects of steric hindrance and nucleation of long-chain structures.
Indeed, the source models for the mainshock (e.g., Asano and Iwata 2016; Kubo et al. 2016) suggest simultaneous right-lateral strike-slip shear movement complemented by normal dip-slip movement of the Futagawa fault segment.
The occurrences of decorative material contaminants in the enamels, such as the tin-rich and iron-rich inclusions identified in the blue enamel and the lazurite particle in the white enamel, also suggest simultaneous application and firing of the various decorative materials.
There was a trend for cultured TRAP and CS responses to correlate, perhaps reflecting their differences in intrinsic immunogenicity but suggesting simultaneous exposure.
One individual (TS148) harbours only 16S rRNA sequences with <98% identity, indicative of colonization by an unknown species from the Akkermansia genus, whereas four individuals (TS1, TS6, TS51 and TS150) harbour both A. muciniphila and other Akkermansia spp. 16S rRNA sequences, suggesting simultaneous colonization of these hosts by different species from this genus.
These characteristics suggest simultaneous exposure to a rodent source.
The data suggests simultaneous breakdown of hemicellulose, cellulose and pectin.
Multiple inhibitors blocked ERK activation, suggesting simultaneous use of multiple pathways and complex signaling web interactions.
This suggests simultaneous inhibition of Ras/MAPK and Rho/actin signaling as a treatment strategy in hHCC therapy.
NUPTs also tend to be located close to each other, suggesting simultaneous integration and/or biased integration preferences.
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