Whether these sites are functional remains unknown, nevertheless their frequent location near transcriptional start sites suggests functionality, and will allow for investigation into the potential hypoxic regulation of genes in their vicinity.
Computer calculations using X-ray data of known PTPases as a basis for homology modeling then suggests functionality that needs to be addressed in developing selective PTPase inhibitors.
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(The very fact that each of these candidates was highly conserved, yet not perfectly conserved, in other species suggests functionality).
Cells expressing these Gap1 forms (e.g. Gap1-141) grew normally on Cit and Phe media (suggesting functionality) and also on Pro + D-His medium (suggesting non-functionality) (Fig. 2).
The immunofluorescent labeling of abundant leukocytes, which may include macrophages, lymphocytes and granulocytes, attaching to Bruch's membrane in the old animals extends our gene expression and protein profiles to suggest functionality.
All the observed behaviors of the isolated elements suggest functionality of these elements.
Over 90% of sequence variants detected this way are transcribed to messenger RNA suggesting functionality [ 13].
In our study, we have shown that about 82% of the original TF-gene binding pairs suggests functionality.
aAlthough atp6 and rpl16 of Asclepias syriaca are annotated in GenBank as pseudogenes, new analyses suggest functionality for both genes.
