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As Supekar and colleagues suggested for functional connectivity (Supekar et al. 2009), the decreased number of streamlines for short and intramodule connections in this study could be due to weakening of local connections through synaptic pruning and neuronal rewiring.
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Herein we found CHH methylation (mediated by PpDNMT3b) to be preferentially targeted to CWH sites (Supplementary Fig. 5), suggesting for functional conservation of CW methylation between mammalian and moss DNMT3s.
The fold-enrichment cut-off suggested for DAVID functional annotation is 1.5 [ 61].
Under this assumption, the particular hypomethylation effect in drm1drm2 (Fig. 4a top panel) suggests for some functional redundancy between DRM1 and DRM2.
In fact, recent ChIP-seq genome-wide studies have shown that lamin A/C contact euchromatin18,19 and have suggested a functional role for lamin A/C in creating a permissive environment for gene regulation18.
These findings suggested impaired functional anatomy for top down and bottom up processing in AD patients.
This study provided new insights into the treatment-related neural responses in MWoA patients and suggested potential functional pathways for the evaluation of treatment in MWoA patients.
Our study provided new insights into the treatment-related neural responses in MWoA patients and suggested potential functional pathways for the evaluation of treatment in MWoA patients.
Previous comparative studies have suggested several functional explanations for interspecific variation in both the total time spent asleep and in rapid-eye movement (REM) or "quiet" (non-REM) sleep.
Subsequent studies suggested a functional role for H63D mutation [ 3, 5, 6].
These data suggested differential functional properties for these two ITAM-like tyrosines.
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