Sentence examples for suggested downstream from inspiring English sources
Informants from other cities had a mixed approach, although they referred to the wider determinants as the causes of health inequalities, they also suggested downstream interventions to address these.
71, 73 Other suggested downstream targets of PDK1 in breast cancer include SGK-3 (which was required for tumorigenicity in a subset of PIK3CA mutated breast cancer cells), p70 ribosomal kinase (an AGC kinase that can be directly phosphorylated by PDK1), and PLCγ1 (which directly binds to PDK1 and regulates cellular invasion in a PDK1-dependent manner.
Previous report on the discovery of ANGPTL receptor, LILRB2, suggested downstream activation of CAMK (calcium/calmodulin-dependent protein kinase -2 and -4 and subsequent recruitment of SHP-2 (a Src homology 2 domain containing non-transmembrane protein tyrosine phosphatase) in freshly isolated mouse spleen cells (Zheng et al., 2012).
The research literature suggests downstream benefits from the proposed wage increase, such as improved health outcomes for both workers and their children, and increases in children's school achievement and cognitive and behavioral outcomes.
Regulation overview suggests downstream regulator elements for DXR-mediating light response in the class of transcription factors, protein modification and protein degradation (Additional file 7: Table S6; Additional file 8: Figure S2).
In contrast, a significant number of genes showed coordinate down-regulation, suggesting downstream involvement in common pathways.
In addition, our findings suggest downstream differences in the intrinsic pathway of apoptosis triggered by diverse antineoplastic drugs.
Of interest, it has recently been shown that the MET receptor activating phosphorylation site was highly responsive to EGFRvIII levels in glioblastoma cells in vitro, suggesting downstream cross-activation of MET by mutant EGFRvIII (Huang et al, 2007).
Several studies have suggested that downstream signaling is regulated by the trafficking of these receptors.
Our results suggested many downstream proteins of BR signaling are induced by phosphorylation via various kinases, not through transcriptional regulation.
The high expression of TaHYD1 in later stages also suggested high downstream synthetic capacity to some degree, which is more preferred to the β,β-branch [ 25].
