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Through a wide range of UEMs that involve users' design feedback have been suggested, current knowledge on users' design feedback is fragmented; in part, because the literature on relevant UEMs often do not present detailed empirical data on the quality of users' design feedback (e.g. [2, 13, 31]).
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Its underutilisation and often incorrect use within general practice appears to be related to lack of time, but also suggests a current knowledge and skills deficit.
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This suggests that the current knowledge of the signaling process is incomplete and there should be other (currently unknown) regulatory relationship(s) in the network that could lead to the accumulation of ATF4 and finally lipoapoptosis.
Computational prediction suggests that our current knowledge of imprinted genes is an underestimate [ 4].
This observation suggests that our current knowledge on adaptation to methanol is far from complete.
In conclusion, this review suggests that, based on current knowledge, the pros of blocking CGRP in migraine patients exceed the cons.
Current knowledge suggests a high redundancy of soil organism communities, i.e. saturation of function at low levels of species richness.
Nevertheless current knowledge suggests that the apoptotic machinery should interact functionally with key decision-making components of cellular metabolism (Colell et al., 2007; Ferraro et al., 2008) cell growth and cell division.
Current knowledge suggests that the periosteum, a fibrous tissue which covers the surface of all bones, contains a population of progenitor cells which mediate the repair of bone defects.
Current knowledge suggests that methionine synthesis is dependent on vitamin B12 enabling the conversion of extracellular 5-methyl-THF into polyglutamate THF, which is utilized in nucleotide synthesis, and that therefore, folate and vitamin B12 levels should be managed in rations (Sirotnak and Tolner 1999; Chassaing et al. 2011).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com