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Boyle and colleagues later extended these analyses of the RCTs reporting hazard ratios of 0.88 (95% CI 0.80 0.97) for glargine versus comparators, but suggested caution should be exercised in overinterpreting the results as indicating a small benefit (39, 40).
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Several limitations to the present study suggest caution should be exercised in interpreting our results.
Our findings suggest caution should be taken in adopting this approach.
We find that the method of rounding real-time QPCR measurements can potentially lead to mis-scoring of copy number genotypes and suggest caution should be exercised in interpreting QPCR data.
Onychophorans and arthropods share ocellus-like eyes (although arthropods also bear compound eyes) [ 37, 38], but our results suggest caution should be used when making inferences regarding lobopodian 'eyes'eyes
This response level suggests caution should be exercised in extrapolating the findings to the whole body of UK surgeons as the opinions of non-respondents may differ from those of the respondents.
However, the heterogeneity of the post-critical illness population, which may include patients with no significant pre-existing chronic disease, suggests caution should be used in applying standard education topics.
The authors suggest caution should be applied if the original version of the DREEM (50 items) is to be used, given the low PSI values for the majority of the subscales.
The variation in fluidity estimates found in small subsamples of sequenced genomes suggests caution should be applied in attempting to establish when we can reliably say that the fluidity of a particular species is greater than that of another.
Our study warns that increased resistance to mutational therapies may simultaneously select for RNA viruses that have a greater potential to adapt to future therapies, suggesting caution should be heeded when considering the usefulness of such interventions.
Improvement in the primary endpoint suggests that memantine may be beneficial to people with FXS; however, the small sample size makes interpretation of efficacy difficult, and the increase in significant irritability observed in two of the six patients suggests caution should be used before expanding its use in this population.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com