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One look at the chest X-ray, which she thought was not normal, suggested a problem in the lower half of the right lung, and that made her think of Lady Windermere syndrome, which is most commonly found in that part of the lung.
Sauk et al. [ 13] suggested a problem in the epithelial component of the developing tooth germ, in which the invagination of the root sheath occurs too soon, and in a sequence of futile attempts to correct itself, results in abnormal dentin formation.
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Ms Hayman also pointed out that for teenagers, engaging in risky or rebellious behaviour was perfectly normal and did not necessarily suggest a problem in their personal lives.
This idea contrasts earlier reports from Helland and Asbjornsen [14], Brosnan et al. [15] suggesting a problem in shifting attention at a higher level.
Several Glutathione-S-transferase encoding genes on the microarray were down-regulated after untreated WCR feeding (Table 1, Table S2) which may suggest a problem in the plant with detoxification of toxic substances from the insect or bacteria.
The hetero-oligomer that is formed with the double mutants and the wild type Cry1Ab toxin was severely affected in membrane insertion and pore formation activity suggesting a problem in the transition from pre-pore to pore as was previously proposed for anthrax DN mutants [16].
At the transcriptional level we show abnormal expression of these two genes in ALS hMSC by quantitative real time-PCR (qRT-PCR) and Western blot suggesting a problem in the regulation of these genes in ALS.
In this patient, we have observed significant reduction of serum VEGF after removal of the primary tumour (Kaya M et al, unpublished observation), suggesting a problem in tissue staining procedure or the quality of the tissue sections examined.
HCT116 cells, which are deficient in MLH1 and MSH3, complemented with MLH1 through the addition of chromosome 3 have been shown to demonstrate mononucleotide repeat stability but still a low level of dinucleotide and a high level of tetranucleotide repeat instability suggesting a problem in MSH3.
Seat vibration suggests a problem in the back of the car.
A vibration felt in the steering wheel suggests a problem in the front of the car (most likely in the steering linkage or the wheel alignment).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com