These findings suggested the triggering of unique signaling pathways in metastasis for homing of breast-cancer cells to congenial environment of specific organs.
The second encounter also suggests the triggering of the monolith's radio signal to Jupiter by the presence of humans, echoing the premise of Clarke's source story "The Sentinel".
Our results indicate that prolonged ER stress caused cell toxicity, inhibited colony formation, induced cleavage of PARP and caspase 7, and decreased the Bcl2/Bax ratio, suggesting the triggering of apoptosis.
This serum protein functions both as a protective anti-protease and a crucial anti-inflammatory factor [ 66], suggesting the triggering of a protective mechanism within Dp427-lacking tissue in response to neuronal degeneration and brain inflammation.
According to our findings (in particular the presence of hemosiderin-loaden macrophages), we suggest that the trigger of the chronic inflammation is small bleeding into the Teflon felt at surgery.
This comparatively fast response was in contrast to the general 12 24 h required for attachment and metamorphosis in response to live CCA [20], [30] and suggested that the trigger of larval attachment is either separate from metamorphosis per se, or is bypassed [33].
Recent studies suggest that the triggering of IL-1β release from leucocytes lies at the heart of a cascade of processes that involves multiple cytokines and mediators.
In light of the results presented here, we would suggest that the triggering of NSD (and associated mRNA decay, proteolysis and ribosome recycling) occurs following the slow translation of iterated lysines and ribosome sliding events.
Together with lesion experiments [2], these findings suggested the simultaneous triggering of excitatory and inhibitory processes by noxious mechanical stimuli, the former triggering the neuronal firing of met-enkephalinergic neurons through a spino-bulbo-spinal loop and the latter blocking such a firing at a segmental level.
A transient increase in tyrosine phosphorylation of multiple proteins was evident 5 min post-irradiation, but no longer detected after 10 min (Figure 2A and 2B), suggesting the rapid triggering of tyrosine kinase activity upon irradiation.
