Exact(4)
These results suggest surrogate surfaces can be used to measure Hg dry deposition; however, extrapolating the results to natural surface can be challenging.
We anticipate that the identification of disease-specific genes will provide opportunities to develop early diagnostic measures, suggest surrogate markers of disease progression, and supply targets for therapeutic discovery.
As a result, the EASL-EORTC clinical practice guidelines also suggest surrogate measurements for the diagnosis of portal hypertension, including platelet count below 100,000/mm associated with splenomegaly and oesophageal varices [ 12].
Discovering molecular correlates is important in cancer research, because it may: (1) provide clues to pathogenesis; (2) propose or support the existence of a new molecular subtype; (3) alert investigators to be aware of potential confounding in association studies; and (4) suggest surrogate markers in clinical or research settings.
Similar(56)
Mental stress reliably induces increases in salivary alpha amylase (sAA), a suggested surrogate marker for sympathetic nervous system (SNS) reactivity.
Nonetheless, the Buck-14 signature contains individual genes like CXCL13 (ligand for the chemokine receptor CXCR5) that correlate significantly with each of the IR-7 genes, suggesting surrogate representation of the IR-7 index within the Buck-14 index, in addition to prognostic features not previously linked to immune/inflammatory or cytokine responses [ 22].
Moreover, the suggested surrogates to identify LBW newborn should be validated in the field setting.
There is evidence to suggest that surrogate parameters, such as the forced expiratory volume in one second (FEV1), do not correlate with patients' well-being [ 4].
Then they had to suggest potential surrogate endpoints for OS in each of the following tumour sites: oesophagus, stomach, liver, pancreas, biliary tract, lymphoma, colon, rectum, and anus.
We also suggest that surrogate outcomes such as changes in risk factors are not used for assessing the benefits of health checks.
These findings emphasize the immense turmoil experienced by family members and suggest that surrogate decision makers could be temporarily incompetent, raising issues about the shared decision-making model [ 2].
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