ADC (b) demonstrates subtle corresponding increased signal, suggesting mildly increased diffusivity.
On heterologous expression of the mutant receptor in CHO cells, a similar pattern was often, though not invariably, seen, suggesting mildly impaired proreceptor processing (Fig. 2b).
Despite collectively compelling genetic, clinical and biochemical evidence for its pathogenicity, loss of function in conventional in vitro assays is subtle, suggesting mildly impaired receptor recycling only.
At Stage 41, using the myofibre-specific 12/101 antibody, a lack of clear separation of skeletal muscle fibres at somite boundaries was apparent in morphant versus CTL MO-injected embryos (Fig. 5G and H), suggesting mildly dysmorphic myotome formation.
Wouldn't he, I suggest, be mildly disappointed if the Daily Mail didn't describe his work as controversial?
The lobby corridors, whose ceilings are festooned with thousands of sharp-edged metal prongs, suggest a mildly outlandish hotel in the Emirates.
These results suggest that mildly elevated 17-OHP does not exclude the possibility of classical 21-OHD.
Essentially, the authors suggest that mildly deleterious synonymous substitutions in protein-coding genes related to neurodevelopmental functions change the efficiency of translation process.
However, since ABL expression (which is equivalent to BCR-ABL expression because probe sets are taken from the 3' end) is minimal for the cured BCR-ABL patient in 3 out of 4 probesets with P <.0.06 differences between leukemia subtypes, Fig. 5 does suggest (very mildly) that Gleevec combined with standard therapy could be beneficial, i.e. that BCR-ABL may be conditionally or partially critical.
