The δ j/ δ̄ value (from Step III) for rare allele 3 was 4.205, which is much larger than the suggested highly significant critical value of γ = 2.5, indicating that rare allele 3 is strongly associated with obesity as measured by BMI.
Furthermore, for this subgroup both the fixed effect and random effects estimates suggest a highly Significant and substantial detrimental effect of neoadjuvant chemotherapy.
Together these data suggest a highly significant association between AD-containing TNC isoforms and breast cancers in younger women (age ≤40 years), which may have important functional significance in vivo.
However, the correlation between leaf traits measured under greenhouse and field conditions was low and not significant, suggesting highly plastic responses of the leaf traits to the field environment.
Both ppk1 and ppx also showed strong negative correlation along this axis and results of generalized linear models suggested a highly significant negative correlation between their abundance and available Pi concentration.
In addition, the maximum pair unique score for all pair-wise relationships was that observed between CGSSa00 and MRSA252, suggesting a highly significant degree of relatedness.
Logistic regression analysis for all-cause mortality at 30 days suggested a highly significant difference between AKI groups in all models, showing that patients with a higher stage of AKI had an increased likelihood of death.
The quantitative modeling suggests a highly significant relationship between ZNF42 expression and other genes in the retinoid-signaling subnetwork, which provides confidence that its alteration was indeed due to activation of the retinoid-signaling pathway.
Of the four target miRNAs evaluated after normalisation to different references, the choice of reference gene did not influence the relative quantity of miR-31 (p < 0.001) between tumour and normal tissues suggesting a highly significant differential expression of miR-31 in CRC.
Even enforcing a stringent false discovery rate (FDR, 0%) and a conservative fold-change (FC) threshold (2-fold), a large number of differentially expressed genes (DEG) was obtained, with 2,351 up-regulated and 1,610 down-regulated transcripts (see Additional file 1 and Additional file 2), suggesting a highly significant difference in expression profiles between group A and group B in Figure 3B.
