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Other views suggest gain of toxic function by PrPSc due to sequestration of PrPC-associated metals within the aggregates, resulting in the generation of redox-active PrPSc complexes.
Our data suggest gain and loss of entire toxigenic plasmids in addition to horizontal transfer of the pathogenicity locus.
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All the surveys in tech spending plans suggest gains of just 1% to 4%.
We suggest gaining the necessary data in the course of the agronomic evaluation of the GMP in relevant and representative locations of the different receiving environments.
Moreover, the C35Y mutation in hMC1R has been associated with red hair color (55), suggesting gain of function.
The analysis suggested gain of RNO12q11, and loss of RNO5q32 and RNO6q21 as the earliest events in mammary tumorigenesis in this material.
Analogously, in the motor domain van Elswijk and colleagues [ 12] presented data suggesting gain modulation of motor evoked potentials being related to instantaneous phase of corticospinal beta oscillations (around 20 Hz).
An oncogenetic tree analysis based on the BAC CGH-array data suggested gain of rat chromosome (RNO) band 12q11, loss of RNO5q32 or RNO6q21 as the earliest events in the development of these mammary tumors.
ASOs will not alleviate loss of C9orf72 function, but as discussed above, the weight of evidence currently suggests gain of function is likely to be the primary mechanism to address therapeutically.
She also suggested gaining a small edge by using distributions to pay estimated income taxes, having the money directed to the I.R.S. late in the year but being credited for having been paid throughout the year.
The party's economic spokesman Patrick O'Flynn has suggested gains from leaving the EU and cutting the aid budget would help.
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