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Because a TF's binding does not necessarily suggest function, additional functional data is obviously useful to further improve the model's performance.
Finally, binding does not always suggest function.
The combination of sequence complexity and disorder propensity could suggest function as well (see section 5.3).
Although these have not yet been studied in V. fischeri, their genomic context suggest function in some cases.
We scrutinised our set of annotated translated smORFs for bioinformatic markers, which might further suggest function of smORF peptides.
Our results show that SAPK4 regulates ion homeostasis and growth and development under salinity and suggest function of SAPK4 as a regulatory factor in plant salt stress acclimation.
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There are marriages that suggest functioning partnerships and others that survive against the odds.
These previous reports suggest functions of these genes during the inactive period for the cambium.
Several studies suggest functions in the metabolism of the different RNAs.
Various recent publications suggest functions for HDACs in cancer formation and progression (Ozdag et al, 2006; Nakagawa et al, 2007).
It can also identify, or suggest functions for, additional genes related to the pathway (e.g., folM).
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