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The data suggest a significant component of IL-1 inhibition of rabbit chondrocyte proliferation is effected through p38 MAPK-mediated actions.
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Cumulatively, these data strongly suggest a significant biological component in GNP radiosensitization; however, the exact cellular mechanisms remain to be fully elucidated.
Our findings strongly suggest that a significant component of the neurological dysfunction seen in Lowe syndrome is due to defective clathrin-mediated trafficking of receptors.
These data suggest that a significant component of the increased SV and CO associated with fluid loading is due to mechanisms that are unrelated to an increase in ventricular preload and the concomitant Starling response.
These studies have also highlighted difficulty in predicted cellular radiobiological responses mediated by GNPs, based on physical assumptions alone, and therefore suggest a significant underlying biological component of response.
This suggests that a significant component of the track bias in the RAMS model is determined by model inherent uncertainties that cannot be removed with the TCB method.
This suggested that a significant component of the cytokine polarization of responses to iNKT cell activating glycolipids in vivo depends on the extent to which IFNγ and potentially other proinflammatory cytokines are produced by other leukocytes that undergo transactivation downstream of the initial iNKT cell stimulation.
This suggests that a significant component of the geographic variation in mRNA abundance in the fly head is influenced by circadian regulation.
Even though the timing of this change remains speculative, the pattern of AGD increase during infancy suggests that a significant component of the remaining perineal growth is likely to occur at puberty along with growth of the external genitalia.
Blocking mitochondrial ATP production by oligomycin significantly decreased cellular ATP levels under all conditions suggesting that a significant component of the ATP production in Rab25-expressing cells is through oxidative phosphorylation (Fig 2F).
The increased risk in specific breeds suggests a significant genetic component, influencing the power of mapping the genetic risk factors underlying SLO.
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