It is plausible to suggest that a large component of the 'inhibition' condition in the Go/NoGo task is recognition of the cue to stop, a process that is very similar to identifying a learnt target stimulus.
Surprisingly, because we observed a large overlap of transcriptional shifts induced by resveratrol and CR in all organs examined, our findings also suggest that a large component of the transcriptional program induced by CR may be independent of CR-mediated alterations in plasma IGF-1, or insulin.
These results suggest that a large component of the age-associated gene expression changes may reflect infiltrating cells (Figure 4B), but that substantial changes are also intrinsic to the aging process of the smooth-muscle/fibroblastic stroma and not from differences in numbers of infiltrating leukocytes (Figure 4A and Table 1 and Table 2).
These and other investigations suggest that a large component of the RNA found in fluids is extremely stable.
For example, high-resolution analysis of human Y-chromosome haplotypes suggested that a large component of a present-day Asian gene pool originates from Eastern Africa and that Asia was the source of a back-migration to sub-Saharan Africa [ 24].
The 2002 and 2007 NHIS CAM Supplements indicate more users of homeopathy than of acupuncture; however, there were more visits to acupuncture practitioners suggesting that a large component of homeopathic use is for self-care.
This conclusion agrees with recent work on human oocytes, which has extensively screened both polar bodies and suggested that a large component of the maternal age effect is due to segregation errors arising in MII (Fragouli et al., 2011).
North Africa, the Middle East, and Northwest China have large relative decreases in PM2.5, suggesting a large dust component to regional PM2.5.
One recurrent observation is that most disease-associated variants occur in non-coding parts of the human genome, suggesting a large non-coding component in human phenotypic variation and disease.
12 As has been suggested in earlier studies, 13 a large component of the currently increasing diabetes prevalence globally may be due to increased diagnostic activity, detecting milder diabetes cases earlier.
