†Virus and host reference groups were selected as those for which sample size was sufficiently large and symptomatic infection was moderate (see Figure 1).
However, only 33.3% of seropositive persons in that study had a compatible febrile illness, and none of these symptomatic seroconverters were sufficiently ill to require medical care (3 ).
These guidelines suggest that benefits of prophylactic antithrombotic treatment outweigh potential risks only in patients who are at sufficiently high risk of developing symptomatic VTE [ 4, 5].
Ideally, a comprehensive decision model for PD that can be applied to different treatment strategies should consider a large spectrum of clinically relevant outcomes and complications of the disease during a sufficiently long time horizon, including reduction of symptomatic progression; initial symptomatic improvement; or reduction of adverse effects, and improvement of HRQoL.
In high transmission regions, where people receive more than one infective bite per day (Arnot 1998; Beier et al. 1999; Hay et al. 2000), does radical cure of a symptomatic infection have a sufficiently large clinical beneficial effect to offset the greatly enhanced exposure of parasites to drugs?
For obvious reasons, we formulated the following exclusion criteria, although patients met the mentioned ICD-10 diagnoses: specific reason for back pain, based on a clear cause or diagnosis, which could sufficiently explain its extent (e.g. radicular symptomatic, myelopathesis, inflammatory changes in the spinal column etc).
Sex-selective abortion is symptomatic of societies in which women are sufficiently marginalised, socially, economically, or politically, that people believe it is better for them not to be born.
As PANSS scale provides ratings investigating not only symptom severity per se but also functional impairment, a score of "mild" or better (i.e. 3 points or less) at all eight "core" symptoms was considered sufficiently representative of a level of impairment consistent with symptomatic remission of the disorder [ 7].
We are therefore unsure of the validity of our figures for self-reported screening participation; it may be that information given to women about the reason for mammography is not sufficiently clear and that the distinction between screening and symptomatic presentation, which is often investigated with mammography, needs to be more fully explained.
