He added: "I have had to put in place special measures to ensure that other officers who may have to deal with Bleakley are sufficiently selected and protected".
Background selection is primarily mediated by the deleterious mutations that are sufficiently weakly selected that they are able to persist to appreciable frequencies but accumulate to increase the extinction probability of linked neutral and beneficial mutations.
Simply put, the nearly neutral theory posits that there exists a significant class of alleles that are sufficiently weakly selected such that the evolutionary dynamics are governed by both drift and selection.
However, as much as 33% of nonsynonymous mutations are sufficiently weakly selected to segregate at low frequency in the polymorphism, which is much greater than usually reported.
We conclude that, despite historical differences in N e for the two species, most newly arising nonsynonymous mutations are sufficiently strongly selected that these differences have played little role in the dynamics of protein evolution.
We estimated that one-quarter of amino acid-changing mutations behave as neutral in O. edulis, and as many as one-third are sufficiently weakly selected to segregate at low frequency in the polymorphism.
This finding suggests that climates in the southern midcontinent were not sufficiently arid to select for C4 photosynthetic pathways over C3 photosynthesis in the late Miocene.
Outside of the lab, in the soil and rhizosphere, the benefits associated with these deleted genes are likely to be sufficiently significant to select for their retention.
A reasonably large n is chosen to select sufficiently broad terms, while terms that annotate many genes simply because of their children terms are automatically discarded.
Nevertheless, no biomarker investigated so far was felt sufficiently robust to select for the use of erlotinib in the maintenance or refractory setting.
To what extent DNA fragmentation decreases reproductive results is undetermined and conflicting results are available (Payne et al., 2005; Niederberger, 2011) although it seems sufficiently justified to select DNA-intact sperm for use in ART to improve results.
