Exact(11)
The agreement between the calculated and experimental values is not sufficiently quantitative but reasonable.
Mathematical modeling, perhaps the most basic tool in systems engineering, is a technique encountered in any branch of science that has become sufficiently quantitative.
Conventional genetically engineered mouse models enable the study of tumor growth in vivo, but they are neither readily scalable nor sufficiently quantitative to unravel the magnitude and mode of action of many tumor-suppressor genes.
However, the examination in this report is not sufficiently quantitative to determine evaluation criteria for volcanic risk assessments, and further work is necessary to quantify the geochemical evolution of the various magma systems reported herein.
Attempts to determine the presence of an uncoating defect as a decrease in viral cores by confocal microscopy or an increase in naked DNA by real time PCR were not sufficiently quantitative in S2 cells (ZB, unpublished).
However, such movies and kymographs (of selected foci) do not give a sufficiently quantitative overview of the effect.
Similar(49)
One hurdle is the technical difficulty associated with generating sufficiently comprehensive quantitative datasets for large numbers of system variables, across different levels of organization.
Although sufficiently detailed quantitative data are hardly available, the halictid bee Lasioglossum malachurum can serve as one example of this type of colony dynamics.
While FRET microscopy is in widespread academic use, it has yet to see significant uptake for drug discovery owing to the difficulties associated with acquiring sufficiently robust quantitative data.
Provided there are sufficiently rich quantitative data sets avaliable to characterize the model, the use of the methodology here shown can be extended to more complex regulatory networks, involving multiple targets, cooperating TFs and miRNAs and signaling pathways displaying cross-talk via post-tranlational modifications.
This study demonstrated that measuring changes in fluorescence anisotropy of the tag on an ABP as it binds its target can provide a sufficiently sensitive and quantitative readout of labeling to allow HTS [9].
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