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Italian Catholic magazine Famiglia Cristiana said the film would damage Pius's already fragile reputation because it was overly apologetic and not sufficiently based on historical documents that defend him.
Efforts to reduce child labour have had mixed success, partly because programmes and policies were not sufficiently based on the realities of the lives of children and their families, partly because of a lack of evidence of effective interventions.
Robust scientific conclusions derived from randomised controlled trials or epidemiological studies are too scarce to inform practitioners' decision-making in many areas of practice and many guidelines are not sufficiently based on evidence and are of low quality.
An additional problem in Spain is the fact that the majority of health care plans offer unrealistically long lists of objectives which are often not sufficiently based on available epidemiological and cost-effectiveness evidence, and their efficacy is seldom evaluated.
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Ultimately, then, the novel's weakness is that none of its characters are sufficiently base: even the villains have noble goals.
If the new equipment is sufficiently well based on existing design techniques and seems to involve few enough technical uncertainties, the issue becomes unimportant.
Even in these cases, we expect the computation time to be sufficiently short, based on the assumption that measurement data will be post-processed with the computational power of a modern desktop computer.
In this paper the process has been simulated in detail with a one-dimensional pseudo-homogeneous reactor model (PHM) and a reduced model has been developed (computationally enormously much faster and still sufficiently accurate) based on a sharp front approach to simplify further reactor and process design and optimization.
While the leading marker, CEA, has been used extensively to determine prognosis and to monitor disease progress and therapy after curative resection, it is not sufficiently specific based on its elevated level in other conditions, such as hepatitis, pancreatitis, inflammatory bowel disease and obstructive pulmonary disease, as well as pancreatic, gastric, lung and breast cancer.
This treatment was continued until the atelectasis had improved sufficiently, preferably based on the chest X-ray (CXR) of the next day.
On the other hand, prospective large-scale studies in well-defined study-groups could reveal if the association between intrusive thoughts and quality-of-life outcomes is sufficiently well based for further utilization in studies or clinical interventions.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com