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A day in Dublin, a day in Wisconsin are alike sufficient samplings of humanity — random test cores plumbing the depths of existence.
We found that there are a disproportionate number of edges with influence probabilities higher than 0.99, which is due to the lack of sufficient samplings of propagation events over these edges.
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These data not only emphasise the need to apply appropriate PK/PD models with sufficient sampling-time points for the accurate estimation of complete concentration-time profiles, but also has direct clinical relevance in view of the fact that relationships between drug exposure and effect (i.e., toxicity and efficacy) were previously poorly defined (Mathijssen et al, 2001).
Hence, we conclude that, to understand the contribution of genetic and (shared) environmental influences to variation in basal cortisol levels, future studies should be designed more rigorously with strict collection and sampling protocols, sufficient sample size and repeated measures across multiple days.
Increasing sampling frequency and/or targeted high flow sampling are more efficient approaches to ensure sufficient sampling and to avoid poorly performing models, than increasing calibration period length.
Of 60 randomly selected men, 53 had sufficient sample volumes in ≥ 3 sampling years (11 missing samples were randomly distributed across sampling years).
The number of sampling events in each subgroup is less than were analysed for mtDNA [ 23] as all events with less than 10 samples were discarded in order to ensure sufficient sample sizes for all nucDNA analyses.
This sampling interval provides a spatial resolution sufficient for sampling the mesoscale variations of the ocean current fields and thus correctly estimating the currents along the tracks (see below).
As long as we generate sufficient number of samplings, we shall be able to approximate well.
The ratio CE/CV, thus, ranged from 0.005 to 0.25, indicating that the precision obtained with the sampling scheme was sufficient for optimal sampling [ 70].
For rare species, sampling using point count approaches is unlikely to provide sufficient precision, and alternative sampling approaches may need to be employed.
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CEO of Professional Science Editing for Scientists @ prosciediting.com