These mechanistic pathways provide sufficient rationale for investigating the hypothesis that use of metformin is associated with reduced risk of selected malignancies.
Subjects in this study had experienced motor and nonmotor signs and symptoms, and were under physician observation for up to a maximum of 5 years prior to ioflupane [I] imaging, which in combination with 1-year post-scan clinical follow-up provided sufficient rationale for using the 1-year clinical diagnosis as a reference standard (standard of truth).
The primary goals of territorial integrity and military supremacy offered sufficient rationale for one or the other of these chiefs to seek even the alliance of their traditional enemy Vijayanagar, particularly in the conflicts between Bijapur and Ahmadnagar.
The new randomized controlled trial provided sufficient rationale for a new meta-analysis on the subject, to provide the best possible evidence regarding the most superior treatment of humeral shaft fractures.
"The fact that the stock is now trading at more than 31 times trailing earnings might have been sufficient rationale for many, but a few more items of note tipped us over the edge.
Given that world GDP grows at 7-8% or so, that is a logical impossibility; eventually mining companies would own all the world's wealth.The moral for investors is that knowing that commodities are rising is not sufficient rationale for buying mining stocks; everyone else knows that.
While women's relationship schemas acknowledged the likelihood that a man will cheat and that women may tolerate partner infidelity to a certain extent, low expectations for monogamy do not appear to provide sufficient rationale for using condoms.
Interestingly, another recent study reported that parents of young children preferred the terms overweight and obese, as long as sufficient rationale was provided for using them [ 20].
Instead of engaging in a careful parsing of the purpose and effect of the "health" regulations, as faithful adherence to Casey requires, and acknowledging the overwhelming medical consensus that neither of the contested regulations promote women's health, the Fifth Circuit said "any conceivable rationale" for the law was sufficient.
While the density of the remodeled loop is not as well-defined as the rest of the protein (Additional file 2: Figure S2C), there is sufficient electron density to provide a possible rationale for the observed improvement in methanol tolerance.
