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Nevertheless, we do sometimes have sufficient methodological grounds for positively affirming the existence of certain things.
In this systematic review, the authors chose a cut-off score for sufficient methodological quality for inclusion based on a study that determined the average score of present items in observational studies in high-quality medical journals, i.e., 69%[24]].
In sum, while we remain open to the possibility that the white matter activations reported here will prove to be artifactual, we believe there are sufficient methodological and theoretical grounds to warrant further investigation.
Too few papers of sufficient methodological rigour were identified.
The most recent review identified 15 studies of sufficient methodological rigor to meet inclusion criteria [ 13].
Only studies with sufficient methodological quality meeting the inclusion criteria were selected for this review.
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There is now a sufficient body of methodological and practical work to support its more widespread use in real applications.
Neither the previous long-lineage study nor the current short-lineage study alone is sufficient to eliminate methodological artifacts from consideration.
Where there was sufficient clinical and methodological homogeneity, we used the xtmelogit command in Stata V.13.1 (Stata-Corp, College Station, Texas, USA) to fit the bivariate model 19 20 to derive summary estimates of sensitivity and specificity and their 95% CIs.
First, previous investigations of ANS function in cancer [ 6, 8– 12, 13, 130 30– 33] often had small sample sizes, did not establish pre-treatment baselines, included a wide age-range of participants and lacked sufficient and consistent methodological and results reporting.
In light of this, the logical first step is not to start an initiative that calls for (external) re-analysis of study results, but would be to ensure sufficient allocation of methodological expertise in the assessment of marketing authorization applications.
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