During the intervention protocol, the intensity of the NMES will be increased to maintain sufficient contraction in order to generated ankle dorsiflexion.
Sufficient contraction of the developing heart requires maturation of myofibrils, composed of repeating units known as sarcomeres, where arrays of actin (thin) and myosin (thick) filaments comprise the contractile apparatus (Clark et al., 2002).
Such fractures can be expected in deposits from hot (for sufficient thermal contraction) and fluidized (for sufficient deposit expansion and subsequent settling) flows, where preservation in an arid environment allows for their unimpeded development.
Dehydrothermal (DHT) treatment alone was not sufficient to resist contraction by the seeded tendon fibroblasts.
It would actually be sufficient to restrict contraction by forbidding only those cases in which the two expressions being contracted have been introduced in semantically different ways.
It appears that the oxidative stress associated with aging chronically activates NF-κB and results in increased antioxidant enzyme activity, but the capacity of aged muscle to stimulate a further increase of ROS during contraction sufficient to measurably alter the GSSG GSH ratio is significantly reduced compared with young muscle [88-90 [88-90
This Ca2+ influx, in turn, triggers the opening of ryanodine receptors in the sarcoplasmic reticulum (SR) and results in a transient elevation of cytosolic Ca2+ sufficient for muscular contraction.
Moreover, the analysis of [14] shows that the Dörfler marking (2.5) is not only sufficient to guarantee contraction (3.4), but somehow even necessary, see Section 4.5 for the refined analysis which avoids the use of efficiency (1.4).
In smooth muscle, MLC2 phosphorylation is sufficient to induce contraction, and in the striated muscle of the heart, phosphorylation increases the rate and magnitude of contractile force (Davis et al., 2001, reviewed in Kamm and Stull (2001)).
Despite numerous studies showing that the fish myocardium contains all the cellular components necessary for the EC coupling found in mammalian heart, it is still unclear whether sarcolemmal Ca2+ influx alone is sufficient to evoke contraction (e.g., 54, 55) or whether internal Ca2+, stored in the SR, plays an active role (58).
That glucose oxidative capacity is not increased in LXRα-Tg hearts may be due to the fact that mitochondrial oxidation rates are indeed normal and not compromised, and since myocardial contractility is unimpaired is evidence that ATP supply is sufficient to fuel contraction.
