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Although the data in both studies (in our opinion) are so far not sufficient, a significant difference trend is recorded.
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Based on a previous study [15, 28] the power calculation showed that inclusion of 20 participants in each group would be sufficient to detect a significant difference of 20% (SD 30%) in biomarker levels with 80% power and a significance level of 5%.
It has been calculated that 27 early end-points will be sufficient to determine a significant difference between the groups.
"Divided amongst 14 health boards, the resource available locally will not be sufficient to make a significant difference.
The four annuals observed (C. pycnothrix, E. tenuifolia, E. fatmensis, and S. verticillata) were not sufficient to produce a significant difference.
Based on the observed rate of mechanism determination of 10% patients in the Before group, we calculated that 17 patients in the After group would be sufficient to show a significant difference of 40%, with at least 50% patients in whom a mechanism could be identified, with a power of 0.8 and an alpha risk fixed at 0.05 in a bilateral situation.
The sample size analysed would have been sufficient to detect a significant difference in predictive value between the TST positive and QFT positive groups at an incidence rate ratio of 1.54 given an incidence rate of 0.60 per 100 person years in the TST positive group.
Again, this was not sufficient to create a significant difference in the total response curve.
A two-sided hypothesis test did not provide sufficient evidence for a significant difference between both volumes of ligation product.
The lower number of animals in our TLR2 study might not be sufficient to detect a significant difference.
Nevertheless, the sample size of the current study was sufficient to demonstrate a significant difference between the interventions groups without taking the time point into consideration.
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