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ISE method suffers a drawback where it is necessary to perform calibration every hour in order to obtain a ±2% reproducibility.
Although the most reasonable approach in most situations, it suffers a drawback: replicating a ChIP-seq experiment will effectively reduce the number of peaks detected.
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However, the policy suffers from a drawback when the land that the government needs is owned by many parties.
The first-order entropy however suffers from a drawback as it does not take into account the image spatial correlation.
Reported studies on the use of SARIMA models for flow prediction mainly suffers from a drawback that, they used a huge historical database for model development.
Meanwhile, the authors emphasise that contrast-enhanced ultrasound suffers from a drawback of "a requirement of the agent injection".
Although this system is sufficient for application by an expert user on a small, laboratory scale, it suffers from a drawback: the inevitable use of an empirical way (examining the biosensor's response data) to identify a pesticide in a sample.
Millipede still suffers a big drawback of mechanical systems.
The most general kind of SPNs with product-form solution introduced by Coleman et al. (and denoted here by SΠ-nets) suffers a serious drawback: the existence of such a solution depends on the values of the transition rates.
BCS class III drugs suffer from a drawback of low permeability even though they have high aqueous solubility.
Although laser devices are commonly used to measure distances and vehicle speed in traffic safety-related studies, they suffer from a drawback known as the cosine effect.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com