Sudden, acute liver failure, which can be rapidly fatal, will almost always trump other, more chronic diseases like that of Ms. Torres.
5 Hepatic toxicity with hyperbilirubinemia was described in one pregnant woman who died of sudden acute liver failure following the administration of AZT/3TC/NFV.
Sudden liver or pulmonary failure and kidney deterioration can result in death.
For HU-status patients the sudden event of liver failure is a dramatic event, where patients are pulled out of their every day life and working position.
The causes of death were: heart failure (n = 44), cancer (n = 9), respiratory failure (n = 5), sudden death (n = 4), liver failure (n = 2), sepsis (n = 2), multiple trauma (n = 2), and renal failure (n = 1).
Acute-on-chronic liver failure (ACLF) is a sudden, severe, life-threatening deterioration of the liver function in patients with a chronic pre-existing liver disease.
In addition, deficiencies in coagulation factors X or VII may indicate bleeding disorders that, without proper therapy, can lead to liver failure, internal bleeding, or sudden death (Morley 2011).
Severe systemic disease such as multiple organ involvements [41], sudden sensorineural hearing loss [42], hypokalemic periodic paralysis [43], liver failure, respiratory failure [44], and renal failure [45] are extremely rare but have been reported.
There was one sudden death and another patient who died from possible treatment-related liver failure 7.0 months after SIRT.
