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A potential weakness of our analysis is that other covariates such as age, weight and gender could correlate to final dose although former pharmacokinetic modelling showed that no such tested covariates provided a statistically significant model improvement [ 11].
Indeed, testing various TPM constituents we found acylnornicotines (hexanoyl- and octanoyl-NN) to exert a powerful inhibition not only of nicotinic responses but also of AITC and capsaicin-evoked CGRP release, whereas the vesicular exocytosis mechanism, as such (tested by K+-induced depolarization), was not impaired (Kichko TI and Reeh PW, unpublished observations).
Similar(58)
Such tests are controversial.
Such tests typically take days.
Unfortunately, no such test exists.
Not all such tests succeed.
AMFm did not require such tests.
There is no such test for truth.
Such tests have long raised regulatory issues.
Developing such tests is not cheap.
NovaNet does not provide such tests.
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CEO of Professional Science Editing for Scientists @ prosciediting.com