Sentence examples for such a conformation from inspiring English sources

The thermodynamic requirements for the formation of such a conformation therefore allows some star sites to be cleaved more effectively than others.

Such a conformation was proposed to obstruct the path for longer RNA chain, due to Pro152 and its surrounding residues.

Furthermore, it would be virtually impossible for other DRFs with significantly shorter linkers to adopt such a conformation (e.g. four residues shorter in human Dia3).

The interactions stabilizing such a conformation could be based on simple complementary interactions between nucleotides of those ribozymes, as suggested by Orgel [61].

As a matter of fact, the catalytic histidine of H. sapiens BChE has never been observed in an alternate conformation, whereas such a conformation is not unusual in liganded AChE.

Although no reverse transition was observed, their simulation suggested the energetic accessibility of such a conformation.

There is no clear precedence for such a conformation-driven assembly.

Such a conformation-based approach circumvents the issue of kinase selectivity often seen with ATP-competitive AKT inhibitors.

Compounds targeting such a closed conformation might therefore deliver SHIP2-specific drugs.

Such a molecular conformation may help impose a preferential order of the rod-like copolymers close to the interface, thus, encouraging stratification.

However, our finding that cysteine substitutions within the region between Asp and Ile were well tolerated, both in terms of channel function and protein conformation as measured by the degree of complex N-glycosylation, suggests that this region of the molecule may not play a significant role in maintaining channel integrity, and is therefore unlikely to be in such a rigid conformation.