Sentence examples for successor compound from inspiring English sources

It was still not a cure, and I told the story of a child who was failed not only by that medicine, larotrectinib, but also by a successor compound.

In August 2006, Cephalon announced discontinuation of modafinil development for ADHD due to safety concerns raised by the FDA, and the company intends to replace modafinil by its successor compound in development, armodafinil [ 61].

Ultimately, the evaluation of MLN4924 and any successor compounds in a clinical setting will determine whether this strategy is a therapeutically acceptable approach.

However, the successor compounds from Bayer, BAY 41-2272 and BAY 63-2521/riociguat (Mittetdorf et al., 2009) were devoid of this at therapeutically relevant concentrations (Bischoff and Stasch, 2004).

Absent reform, corruption of TSERS is likely to cost the state's public workers and taxpayers billions more over the next few years and leave in place a system under which Cowell's successors will compound the financial damage.

The method is based on the condensation reaction between dichloroquinone-4-chloroimide with phenol compounds that do not have a successor group to form a compound of the 2,6-dichlorophenol.

To what extent drug resistance towards this novel compound (and its successors) will follow patterns of drug resistance that are already known or entirely new mechanisms of drug resistance is yet to be seen.

Breathless press coverage has hinted that the compound, or its successors, could one day become life-extending pills for humans.

Radama's widow and successor, Ranavalona I, renovated the Mahandrihono compound and moved several buildings from the sister rova at Antananarivo to Ambohimanga.

As Gilmour admitted, the board made a mistake in appointing Tommy Craig as successor to Danny Lennon last summer, an error compounded by the recruitment decisions that followed.

His successor, King Andriambelomasina, entombed him at the Mahandrihono compound within the rova at Ambohimanga.