As research progresses, the metabolic (and often genetic) bases of these diseases are being successively revealed.
On the basis of profiling analysis of miRNAs in BAT before and after cold exposure, RNA sequencing for differentially expressed miRNAs between satellite cells and brown pre-adipocytes, and through bioinformatic analysis predicting PRDM16 targets, several groups have successively revealed miR-133 as a critical regulator of adipocyte browning [ 26– 28].
After several blackouts that successively reveal Mr. Goldhuber running in circles, or walking forward with bent, turned-out legs, head bobbing like an automaton, Ms. Peterson appears.
Like these moves, the story continues to unfold much like matryoshkas, or Russian nesting dolls, each opening successively to reveal a smaller one nestled within.
When applied at regional and subregional scales successively, BRT models revealed prominent effects of elevation, latitude and distance to salt lakes at large scales, whereas slope, topographic convergence and insolation gained influence at local scales.
Structure runs on successively smaller clusters revealed five distinct geographic clusters of nuclear DNA variation that were largely uniform in their population assignment.
This shot's all about the taillights of a car, successively obscured and then revealed by the twists of the road.
Like a Russian doll, Gone Girl unfolds via a series of revelations, each of which challenge what the reader thought had gone before as skins are successively shed to reveal shocking new identities lying underneath.
Optical properties of the primary concentrator mirror, such as reflectivity as well as tracking and surface errors, are successively idealized to reveal the differences between ideal and real concentrators.
Figures 3e-h show volume rendered representations of the fused image data with the OCT image successively resected to reveal the dermal and subcutaneous vasculature in the PAT image.
Going back more than 30 million years, however, successively greater "virtual pole" distances are revealed, indicating that substantial deviations occurred.
