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In the palliative setting, chemotherapy aims essentially at extending survival and the use of all available drugs (fluoropyrimidines, oxaliplatin, irinotecan, bevacizumab, antiendothelial growth factor receptor (EGFR) antibodies) either successively or concomitantly has increased the median OS of patients to more than 25 months.
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One possible mechanism is that U2AF65/35 binds initially and recruits PUF60, which subsequently or concomitantly displaces U2AF from the RNA.
Patients in the 'both agents' category may have received the anti-HER2 agents either sequentially or concomitantly.
For drilling several holes successively or simultaneously in a workpiece, machines with multiple spindles are available.
At the training session crabs were given the two types of training either successively or simultaneously.
There were 15 bombings in total, before all five George Jackson brigadiers were successively killed or captured as the police noose tightened.
Of all chronic heavy drinkers, only 15 20% develops hepatitis or cirrhosis concomitantly or in succession.
Repetitive compounds elements are composed of sequences in which two or more repetitions (perfect or imperfect) are arranged successively with or without nucleotide bases between them [ 8].
Analog signals, when they are successively copied or manipulated, lose crucial information with each generation.
Then, big efforts are often required when the application has to be successively modified or extended.
Antidepressants were present in 58% of the BD group, of which 39% did not have at least one mood stabilizer or antipsychotic concomitantly present.
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CEO of Professional Science Editing for Scientists @ prosciediting.com