Successive variant frequency and transcript data updates will add to this resource and aim to validate more candidate STEPs.
The figure shows that in runs with recombination successive escape variants appear faster than in the runs without recombination, and that the accumulating effect of recombination increases with the number of escape mutations.
Here, Molineaux and colleagues have actually quantified the relative importance of three types of immune responses (innate, acquired variant-specific and acquired non-variant-specific) over successive parasite peaks, finding, for example, that innate immune responses are almost entirely responsible for controlling the primary peak but are completely absent after the sixth peak.
The variation was tiny, and suggests that the Y chromosome has been pared down to its bare essentials by "purifying selection"An alternative explanation for the low genetic variation of Y chromosomes is that a minority of men had a high proportion of children, passing on fewer Y chromosome variants to each successive generation.
In view of this difficulty, price-collection agencies sometimes rely upon each respondent, usually a business firm, to report prices in successive periods for the same variant of a product (say, men's shoes); the variant chosen by each respondent may be different, but valid data will be obtained as long as each provides prices for the same variant he originally chose.
3 These investigators were able to distinguish ten successive phases in the Ica variant of the Paracas style.
A recent model describing the sequential generation of shorter Aβ peptide variants from longer Aβ peptides via successive proteolysis or "processivity" has been used to describe one potential mechanism of action of GSMs.
However, we observe that the carrier reordering based on reliability measures does not ensure orthogonality of successive regressors; therefore, the low complexity variants of RLS introduced earlier cannot be employed.
Over the last decade, the GII.4 variants were dominated by successive circulation of GII.4/2002, GII.4/2004, GII.4/2006b, and GII.4/2008, with GII.4/2006b continuing to date.
What is needed next is the development of real-time assessments of sensitivity to nicotine based on objective measures [ 41] that can be refined and validated ultimately as phenotypes in successive tests of association with genetic variants.
