Sentence examples for successive therapy from inspiring English sources

Another explanation was the so called "heteroresistance" that means the presence of mixture of susceptible and resistant subpopulation in culture which could be an obstacle against the sensitivity of molecular drug resistance testing and the successive therapy[ 21].

After correction of the paraproteinemia with successive therapy of melfalan-prednisolon and later bortezomib-dexamethason, cholesterol levels restored to initial values HDL-C measurements were initially performed on a Hitachi 917 analyzer (Roche Diagnostics, Switzerland) with HDL-C reagent (HDL-C plus second generation, Roche Diagnostics, Switzerland).

They are characterized by a chronic course of the disease with successive therapies upon occurrence of relapse.

Thus, platinum, taxanes and cetuximab appear to be drugs of choice for the treatment of recurrent and/or metastatic HNSCC, and could be used either in combination or as successive therapies.

His successive antineoplastic therapy consisted of enzalutamide.

Therefore, successive chelation therapy includes the supplementation of ascorbate as reducing agent to increase the availability of storage iron to chelators [ 47].

However, myeloma remains incurable, is still characterized by a decreasing response duration with each successive salvage therapy [ 1], and in the relapsed and especially the refractory settings, is associated with a median survival of 6 months or less [ 25].

We suspect that a reason for this apparent discrepancy of trial data from real-world use is the emerging clinical practice pattern of successive step therapy [ 22, 23], as most prominently illustrated in the Sequenced Treatment Alternatives to Relieve Depression (STAR-D) effectiveness trial [ 9].

However, this model was not consistent with the known clinical observation that select patients with metastatic breast cancer could be maintained on successive endocrine therapies for prolonged periods.

If a patient required more than two successive dose reductions, therapy was dicontinued.

They are included in the present series because they continued vaccination in the presence of active metastatic disease or were referred for successive IL-2 therapy.