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This rise of performance data is the result of successful strain engineering in combination with process optimization.
"It seems to be a very virulent and successful strain" in all susceptible species, says Paul Kitching of the Institute for Animal Health (IAH) in Pirbright, U.K., who heads the world's largest FMD research group.
If the viral genomes from different patients are more or less identical, that suggests a new, more successful strain is breaking out; if the genomes are more diverse, the increase is more likely to be an artifact due to more testing.
The new media space that Raafi describes has fostered a rise of black skaters, black rockers, black gamers and a wildly new successful strain of nerdy hip-hop (Kanye West, Gnarls Barkley, N.E.R.D).
By this reasoning, the A clone is the most ecologically successful strain, able to thrive in a new niche with little genetic change.
Successful strain development integrated with expression vector development and screening, can result in increased expression levels of target protein and in significant gains in process productivity.
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Enforced inbreeding serves to fix and maintain successful strains; outbreeding provides evolutionary diversity that may facilitate habitat or range expansion or may serve to provide flexibility for environmental changes.
The T and Haarlem strains are usually not considered among such successful strains, although they remain highly endemic in most parts of the world [7].
In the case of M. tuberculosis, one of the outcomes of genetic typing has been the identification of particularly aggressive or successful strains.
In conclusion, this work has identified a number of genetic loci which are associated with highly successful strains.
The worldwide clonal dissemination of some successful strains, such as E. coli sequence type (ST 131, is playing a prominent role [ 1].
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