Although methods with limited structural flexibility have proven successful at recapitulating consensus binding sequences from wild-type complex structures, conformational flexibility is likely important for design and template-based modeling, where non-native conformations need to be sampled and accurately scored.
The study design was modeled after previous successful NIH-sponsored consensus conferences for other tauopathies, specifically progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) [ 10, 17, 25].
Still, it is not clear whether this strategy is successful, and no consensus exists on which tumor characteristics are the most useful to predict relapse.
In addition, the process of creating the logic models was successful in building consensus across subject experts on how a measure can be interpreted proactively at the point of care and how to reconcile best practices with small practice workflow.
Successful application of consensus maps for synteny based candidate gene identification and/or definition of QTL location has been extensively used both in cereals [ 59- 62] and in legumes [ 35, 37, 63, 64].
It has been so successful that the emerging consensus is that what may now be needed in Afghanistan is a similar surge of American forces.
Regardless of whether graphitic N, pyridinic N, or both N species are active sites for the ORR, there is a consensus that successful N doping is crucial for electrocatalysis.
Despite many unresolved questions posed by novel and rapidly changing technologies, there is widespread consensus that successful intervention design demands a user-centered and iterative approach to development, using mixed methods and in-depth qualitative research to progressively refine the intervention to meet user requirements.
26 The CHW intervention is based on (1) existing consensus of successful diabetes interventions in vulnerable populations and (2) its promise as a sustainable generalisable intervention.
