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Observed responses for the optimized product agreed with predicted values, demonstrating the success of the optimization procedure.
Finally an experimental campaign is carried out on the two optimized models to validate the computations and assess the success of the optimization process.
The success of the optimization procedure is contingent upon reduction of emission and enhancement of the spraying characteristics.
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Commercial production of yeast, which exceeds 1.8 million tons per year, owes its success to the optimization of feedstock, energy inputs, physico chemical parameters, and chemical engineering innovation.
Because these models are approximate models, the introduction of process model mismatch may have a significant effect on the success of the process optimization.
However, if the integer variable is involved in the highly nonlinear model, the probability of success in the optimization calculation becomes very low because of the big computation load.
The national policies and legislative support on the introduction of exotic species and the level of efficiency in enforcement of the existing regulations play a key role in the success of yield optimization efforts in the countries.
It should be noted that the success of codon optimization in improving the expression is extremely dependent on the optimization strategy employed; recent developments in this field seem to suggest that paradigms that have long been dogmatically adhered to have little empirical basis (Welch et al. 2009).
The reason for the variability in the success of codon optimization is currently unclear but may relate to moderation of translation which could impact protein folding.
The subsequent hit-to-lead evaluation and the success of lead optimization to identify a clinical candidate are critically dependent on the quality of the initial screening hit.
However, the success of enzyme optimization efforts is currently limited by a lack of robust high-throughput (HTP) cellulase screening platforms for insoluble pretreated lignocellulosic substrates.
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