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Finally, it has proved very difficult to transfer success in activating UI benefit recipients to other recipients of inactive benefits, notably those in receipt of long-term sickness/disability benefits.
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OECD (2013c) points out that it has proved hard to transfer the success achieved in activating UI benefit recipients to disability benefit recipients.
These patterns may reflect the success of roots in activating Al tolerance mechanisms and the restoration of the transcriptome to a prestress program, and in the case of the Al-sensitive line of Medicago the failure to establish an adaptive response.
The subsequent root growth recovery and the concomitant reduction in the number of responsive genes presumably reflect the success of the roots in activating Al tolerance mechanisms.
In sum, the OECD's activation reviews have highlighted examples of both success in terms of activating UI benefit recipients (Australia, Japan, Norway, Switzerland, UK) and failures, at least until recently (Finland, Ireland).
The first reported successes at activating C H bonds in saturated hydrocarbons, published in 1982, used organometallic iridium complexes that undergo an oxidative addition with the hydrocarbon.
"We're simply jumping in and activating it".
An adequate design of components to be manipulated by remote handling is a key factor in the success of any activated facility, having a decisive impact on availability, prompt and safe maintenance, occupational exposures and flexibility of the facility.
The success of C1-N1N2 in discriminating activated Rho in immunofluorescence studies implies that this new tool, in collaboration with currently used RhoA and B antibodies, has the potential to analyze Rho activation in cell function and tumor development.
The choice of tumour types and relevant patient population selection would be the key in the evaluation of the success of these compounds activating WT p53 by controlling its degradation and stability.
The recent success in suppressing the growth of cultured lung cancer cells with activating EGFR mutations by siRNA (Sordella et al, 2004) unveiled the sensitivity of siRNA-based approaches in distinguishing drivers of tumour growth.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com