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In a more recent review on CNS neurones, it has been suggested that as more stress is placed on the mitochondria to control stimulation-evoked increases in [Ca2+]i the 'polarization state' of the mitochondria may subtly decline over the lifespan (Toescu, 2005).
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Susan Pourfar has a marvelous turn as Sylvia -- her hearing degenerates throughout the show so Pourfar must subtly show that decline in her speaking voice without seeming too showy.
The fabled Black Forest of southwest Germany, whose dark wooded hills have exerted an almost mystical hold on human imagination since Roman times, is subtly but rapidly declining.
Which touches, finally, on the issue not confronted head-on in this ugly campaign, but played on none-too-subtly by Donald Trump: the decline of white America.
Reduced insulin signalling and DR both alleviated cognitive decline, but in subtly different ways.
And I worry that when people's incomes start declining, it will subtly influence their judgment.
No one captured the sense of an imperial civilization in decline more fully or subtly than the expatriate American novelist Henry James.
He was explaining, indirectly, subtly, and gently, why he had declined to accept the view of Northern friends of his, like Marty Peretz, that the country should drop affirmative action and pursue absolute color-blindness as an ideal.
Rather nicely and subtly, the RBA in noting the declining iron ore prices pauses to give a bit of a slap to state and federal governments over the past decade.
Peter Garrard of the Medical Research Council's cognition and brain sciences unit said: "Alzheimer's is known to disrupt the brain's semantic system, but this can happen subtly before anyone has the remotest suspicion of intellectual decline.
The technique was subtly refined during the Kamakura period (1192 1333), but it suddenly declined in the Muromachi period (1338 1573).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com