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While high correlations among measures can be used to identify obviously important network nodes (e.g., Huang et al. [33]), our structural space approach would be limited if degree and betweenness centralities in semantic networks (including our own) were highly correlated and it would fail to identify subtle roles of network nodes.
While the superoxide radical and SOD have been implicated in many disease states including inflammatory diseases, diseases of ischemia and reperfusion, neurodegenerative diseases, and cancer, as well as more subtle roles in cell signaling and perhaps in immune function, SOD is not yet in widespread usage in human clinical medicine.
This suggested that, like other complex physiological processes such as ageing [28], the transcriptional responses of individual genes play subtle roles in the response to hyperosmotic stress.
Careful delineation of the TNF response in human Tregs will be required to reveal subtle roles of TNF during autoimmune conditions and help to resolve contrasting reported findings.
Another possibility is that our tests were not sufficient to reveal more subtle roles of TRPML3 such as potential modulatory roles in hair cells or other parts of the auditory and vestibular system.
More subtle roles for α− and β−mannosides are found in the glycans of higher organisms, where oligosaccharide diversity affords cell signaling and recognition events that lead oligosaccharides to play the role of "glycocode"; the language of cellular communication [1].
Similar(47)
Some prefer a less strident, if more subtle, role in the chorus.
Speculating about the nature of this subtle role-play is part of the book's fun.
Ms. Anderson said that ever since the first head count, in 1790, the census had played an important if subtle role in reflecting preoccupations and shaping social thought.
But the mayor has also played an essential if more subtle role in nudging the city to gradually let go of its grief.
"Batman is a complex character with the subtle role of a hero just outside of the law," explains Jamie Walker, studio director at Rocksteady.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com