Sentence examples for subtle pathology from inspiring English sources

This may help in detection of subtle pathology and its early intervention.

Most vendors have made the transition to multi-frequency processing algorithms (e.g., MUSICA, UNIQUE, MFP), which better achieve enhancement of low-density structures and subtle pathology [ 50, 51].

Lung PMMR is unlikely to have higher diagnostic accuracy than thoracic MRI in life, and high-resolution computed tomography (CT) remains the mainstay of diagnostic imaging for parenchymal changes, including interstitial lung disease and more subtle pathology.

A thicker left supramarginal gyrus may reflect a subtle pathology; if sustained throughout childhood, a thick left supramarginal gyrus may indicate immaturity or altered development, as the region is expected to overgrow in the first years of life and prune back in childhood and early adolescence (Shaw et al. 2008; Sowell et al. 2004; see also, Porter et al. 2011).

Mice expressing anchorless PrP accumulate high titers of prions and protease-resistant PrP when challenged with scrapie [32], [50], yet develop only subtle pathologies [51].

Notably, histopathology might not be sensitive enough to detect subtle pathologies, especially those associated with variation in cell numbers (Boyce et al., 2010; de Groot et al., 2005) or mild reactive changes such as gliosis (Sofroniew and Vinters, 2010) that require specialized quantitative analyses that are not compatible with large-scale phenotyping.

Now subtler pathologies have replaced more explicit ones.

These data indicate clinically eloquent brain regions, usually deeply involved in the pathological substrate of MS, as those that have a minor degree of subtle myelin/axonal pathology in RIS subjects, providing a compelling reason for the lack of clinical manifestations existing in these subjects.

In view of the endothelium-restricted and developmentally-regulated expression of EHD3 in the kidney, we undertook detailed analyses of Ehd3 /– kidneys to characterize potentially subtle glomerular pathology.

While certain mutant LRRK2 BAC transgenic models exhibit subtle tau pathology or processing abnormalities in the absence of frank neuronal loss [31] [32], [34], our G2019S LRRK2 mice lack obvious protein inclusion pathology that is observed in PD brains bearing LRRK2 mutations, including α-synuclein, tau or ubiquitin inclusions [10].

Until recently, brain research in SIDS has emphasized only subtle hippocampal pathology, consistent with chronic hypoxia [ 6, 15, 19, 39, 59].