Sentence examples for subtle modification of from inspiring English sources

Detailed structure-activity relationships (SARs) studies on the aglycone of compound 1 indicated that the subtle modification of oleanolic acid as an aglycon has key influences on the antiviral activity.

Detailed structure activity relationships (SARs) studies on the aglycone of compound 3 indicated that both the type of pentacyclic triterpene and the subtle modification of ursolic acid as an aglycon had key influences on the antiviral activity.

Our results clearly indicate that agonism and antagonism of the antibody/cytokine receptor chimera can be readily switched by a subtle modification of the ligand binding domain as well as that of GPCRs, also implying the existence of inverse agonism in cytokine receptor superfamily.

In our cases, subtle modification of Fisher's method was introduced to improve lip contour on the philtral ridge; orbicularis oris muscle overlapping.

The action of antifungal agents is modulated by subtle modification of the membrane lipid composition [17].

Some roles of the Tβ4 and Tβ10 couple are linked to a subtle modification of their relative amounts [11].

They are able to do this through subtle modifications of the pattern and fit of their otherwise standard garments.

The installation proceeds seamlessly into a work for two human performers and speakers featuring subtle modifications of breath sounds.

Yes, you read that correctly – millions, although you soon realise that most of these on-the-fly creations are subtle modifications of the usual rifles, pistols, rocket launchers etc.

Although the principles of these salvage techniques are similar to the commonly performed primary surgical procedures, subtle modifications of the approach are sometimes required, and these are emphasized herein.

These results suggest increases in cortical complexity and subtle modifications of sulcal topography of frontal lobe regions, likely reflecting ongoing processes such as myelination and synaptic remodeling that continue into the second decade of life.