Mixed by Kokal's then-boyfriend, former Red Hot Chili Peppers guitarist John Frusciante, it's subtle, involved, but immediately captivating stuff, the result, Kokal explains, of lengthy sessions that "start with somebody having something, whether it's an arpeggio or a bass line or some lyrics.
"It was more subtle, involving conversations with many different people, soliciting and gauging reactions to ideas, and finding creative solutions to meet both the community's goals and our goals as game developers," Vesce said.
The makeovers are often radical, turning white walls crimson or sawing legs off coffee tables; but the drama is usually subtle, involving lots of strained cheerfulness and some grumpiness and grimaces -- rarely tears.
The differences between cancerous and healthy human cells are, by contrast, subtle, involving quantitative differences in gene expression (Zhang et al. 1997).
In some cases (for example, congenital metabolic diseases), it may be possible to identify a single, robust diagnostic metabolite, but in many cases the perturbations are more subtle, involving the activation of multiple enzymatic pathways.
The occurrence of disruptions of reproduction and health that can be clearly attributed to the effects of pollutants is rare, reflecting the fact that effects are generally subtle, involving changes in gene expression and the structure and function of internal organs but not gross changes in health or reproductive performance.
"We haven't been able to exclude that there is some subtle difference involved in how it's made at Greenville," Mr. Tyle said.
Proofs of such statements are usually rather subtle and involved and constitute a large part of the subject of thermodynamics, but conclusions based on thermodynamic principles are among the most reliable results of science.
As Mr. Harteveldt of Forrester said: "This isn't as easy as buying an airline ticket from Point A to Point B. There could be subtle factors involved, such as the category of hotel room you're getting in the package.
Sometimes it's blindingly obvious, as in the way Sarah's behaviour has affected her children, but other times it is more subtle and involved: the idea that Sarah's decision to leave Tammy might have ruined Josh's career, for example.
It also stimulates the discussion on subtle issues involved in the determination and use of elementary powder's properties.
