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In other words, it takes a prepared mind to appreciate the value of a subtle experiment that may have a null result, and a science writer must impart this appreciation to readers, even at the cost of glazing a few eyes.
Wesselmann and his colleagues decided to conduct a subtle experiment to find out.
However, for purposes of intellectual exchange we offer the following thoughts here should the reviewers want to think about it for future work: The most subtle experiment has been done in the Goldstein, Pheasant, and Miller paper in Neuron (1994) where the pyroGlu was mutated to a proline resulting in a near-isosteric but charge inequivalent substitution.
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Such exquisite control of the nano-world allowed them to design subtle experiments probing the meaning of quantum weirdness.
Subtle experiments suggest that as temperatures dip toward absolute zero, crystalline helium can bizarrely flow like a liquid with no viscosity, a phenomenon known as supersolidity.
Similarly effective were more subtle experiments that modified the sequences of two genes, orc1 and kelch13, which have putative roles in gene silencing and emerging resistance to artemisinin, respectively.
In anticipation of upcoming familial discord, the Ativan is flowing and the couches of therapists – whose uncomfortable throw pillows one wants to cast aside but which one worries are actually subtle psychological experiments – are occupied.
The dozens of strips translated here are chronologically scrambled, shuffling Swarte's taboo-popping early work with later, subtler formal experiments.
As it can be difficult to probe some of the more subtle phenomena by experiment, numerical simulations can be illuminating.
It is unlikely that immunofluorescence would be sufficiently sensitive to small changes in overall abundance and those authors performed no quantitative analysis, stating "While it is formally possible that transcription is affected in a subtle way, our experiments allow us to conclude that CHD1 is not absolutely required for the association of elongating PolII on chromosomes".
This differences between the expression of AtWRKY28 [ 116] and BnWRKY28 (this study) in response to ET treatment may be the result of subtle differences in experiments including the use of different tissues (seedlings versus leaves), and/or the ethylene-generating reagents (ACC versus ET) used.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com