MRI of the brain showed mild diffuse volume loss, T2 hyperintensity with subtle restricted diffusion in the pulvinar nuclei of bilateral thalami (pulvinar sign), and subtle restricted diffusion in the right frontal cortex (cortical ribbon sign) (arrows).
In cases of segmental hepatic infiltration, subtle T2-hyperintensity with diffusion restriction can occasionally be seen.
Axial CECT image demonstrating diffuse enlargement of liver and spleen without any evidence of focal hepatosplenic lesions In cases of segmental hepatic infiltration, subtle T2-hyperintensity with diffusion restriction can occasionally be seen.
In contrast to the temporal bistable case, we see a subtle interplay between the bistability, diffusion and signal heterogeneity as well as the previous history of the system.
Multichannel FCS data analysis of Rhodamine 6G (R6G) in solutions with various viscosities illustrates our ability to calibrate each channel and to measure subtle changes in small molecule diffusion due to varying environment.
As conventional MRI is not sensitive to detect subtle damage of the white matter (WM), diffusion tensor imaging (DTI), using the diffusion properties of water molecules might be of use to provide an early marker for this cognitive decline [5], [6].
First, changes in diffusion could be too subtle or restricted to be identified by TBSS analysis.
These differences were seen even in patients with the best outcomes and patients in whom conventional magnetic resonance imaging was normal, suggesting that diffusion tensor imaging can detect subtle injury missed by other techniques.
Recent advances in MRI technology, specifically diffusion tensor imaging, have allowed subtle changes in white matter to be revealed.
