This achievement, which involves some remarkably subtle chains of definitions and logical reasoning, has become known as Frege's Theorem.
Although this change in cavity shape is dramatic, it results mostly from subtle side chain movements and is not the result of large changes in backbone positioning.
Little is known about the biological significance of this seemingly subtle backbone chain-length variation, however, the alkyl-chain length mismatch has substantial biophysical consequences.
The finale, with its dresses in the sinuous metal mesh pioneered by Gianni Versace, was so subtle because the chain mail effect was screened with cloth.
These mice carry a dominant patient mutation in mitochondrial replicative helicase Twinkle, resulting in progressive MM after 12 months of age, with the accumulation of multiple mtDNA deletions in their skeletal muscle and brain, leading to a subtle progressive respiratory chain deficiency (Zeviani et al, 1989; Suomalainen et al, 1992; Tyynismaa et al, 2005).
The subtle sound of chains clinking breaks through the brief moments of silence.
In many cases, subtle changes in carbon chain length, double bond location and isomer blend differentiate the pheromones of closely related species [3].
Chemistry is a subtle science, requiring sophisticated chains of inference in order to make reliable conclusions about the invisibly small details of molecular architecture.
The subtle balance included gilt chains worked as belts, pockets and as a teasing pair of straps holding up one of the snow white evening outfits, where the bodice was cut with twin rounded curves.
Subtle changes of side chains allowed the generation of polypeptides with appropriate DNA binding strength as well as endosomal escape capacity.
