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Amidst their clear commonalities lie subtle but substantial differences as well.
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Microarray experiments have historically suffered from subtle to substantial differences in data produced from the same or similar templates when performed on different dates, by different users, or in different locations [ 28].
iPSCs share the majority properties with ESCs, such as morphology, differentiation, pluripotency, DNA methylation and gene expression; however, there is a wide range of evidence showing that there are subtle yet substantial differences between these cell types [ 17– 22].
Amphibians play subtle but substantial roles in California's ecosystem, eating insects and feeding wildlife.
The declaration would represent a subtle but substantial shift in policy.
She also had a subtle but substantial role in the civil rights movement.
An even more subtle, but substantial barrier is the interface through which representations of plans are made available.
Subtle, but substantial.
Therein lies the subtle, substantial difference Pell Grants can make.
But there are substantial differences.
But there were substantial differences between the two of us.
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