Sentence examples for substrates to help from inspiring English sources

In conclusion, CTX-M-14 residues Ser237 and Arg276 work together in the hydrolysis of β-lactam substrates to help shape the substrate specificity of the enzyme to that of an effective cefotaximase.

This is due to the different alterations of protein structure by which the PA28 and PA700 regulators bind to the 20S proteasome core to help peptide substrates reach the catalytic core beta subunits.

The combination of models to take into account the fracture and buckling of brittle thin films on compliant polymer substrates under tensile strain and to help describe interfacial properties, as in this work, is relatively new.

Substrates were prepared in the same buffer, except that 1% DMSO or ethanol was used to help dissolve the substrates.

This contact is missing in the BphAERR41 dibenzofuran, and strong enough in the BphAERR41 2-chlorodibenzofuran to help prevent suBphAERR41 2-chlorodibenzofurantolytic reaction.

Alternate substrate with layers of hay to help support the tunnel networks and to provide vital chewing material.

Finally, organic solvents were frequently used as co-solvents to help in dissolving substrates in the SrtA-mediated reaction (Madej et al. 2012).

The proposed role for the single Mg2+ ion is to help position the substrate and stabilize the transition state and 3′-OH leaving group.

While the sequence cooresponded to a poorly structured region of the crystal structure, this "trip-wire" loop has been proposed to help stabilize binding of substrate, as well as to possibly close the active site upon substrate binding.

A systematic investigation of the intermolecular interaction between the multidrug-resistant mutants of HIV-1 PR and its substrates would help to establish a complete profile of substrate response to PR mutations and to design new antiviral agents combating drug resistance.

The identification of several optimal OST1 phosphorylation sites in ABFs that are proposed to be physiological SnRK2 substrates indicates that this approach can be used to identify new substrates and also help to localize kinase specific phosphorylation sites on these proteins.