Sentence examples for substrates to guide from inspiring English sources

To this end, we sought to generate cell sheets that have specific ECM/cell organization using micropatterned polydimethylsiloxane (PDMS) substrates to guide cell organization and tissue growth.

To this end, we sought to develop a simple method for generating cell sheets that have defined ECM/cell organization using microtextured, thermoresponsive polystyrene substrates to guide cell organization and tissue growth.

In addition to basic research in extracellular matrix and mechanobiology, manually pulled fibronectin fibers have the potential to be used as substrates to guide cell migration and growth in tissue engineering applications [37].

We considered three major factors to develop our biomaterial scaffold: (1) creating nanotopographically patterned substrates to guide cell substrate interactions; (2) adding heparin gel microstructures to the nanopatterned substrates; (3) embedding stromal cells into heparin gel structures for production and release of soluble cytoactive factors.

We apply an elastic field to the substrate to guide the self-assembly process.

In contrast to Campenot compartmented chambers utilizing Teflon divisions and scratched substrate to guide axonal growth, microfluidic devices are fabricated from PDMS using a photoresist template to create microchannels for axonal growth between compartments (Taylor et al., 2005).

In polyamine oxidase (PAO), a negatively charged 'carboxylate ring' can be found at one side of its substrate tunnel to guide polyamine substrate molecules into the active site (Binda et al. 1999).

Further studies of these enzymes are needed to better understand their regulation, their relative contribution to citrullination in RA and, in particular, their substrate specificity, to guide therapeutic development.

Also, for hAChE, the aromatic residues lining the substrate binding gorge have been reported to guide substrates to the active site deep within the gorge.

KE07, a computationally designed Kemp eliminase that employs a glutamate side chain as the catalytic base for the critical proton abstraction step and an apolar binding site to guide substrate binding, was optimized by seven rounds of random mutagenesis and selection, resulting in a > 200-fold increase in catalytic efficiency.

The information obtained from sialidase substrate specificity can be used to guide the design of new inhibitors that are selective against bacterial sialidases.